COVID-19 : PhenoSwitch wants to contribute to the scientific effort

Posted by Hugo Gagnon Ph.D. on April 7, 2020

Scientists had been warning us

As predicted by the scientific community, the COVID-19 pandemic is hitting the world with full force. The speed at which the infection spreads is absolutely terrifying. However, learning from past pandemics, the authorities have taken measures to slow the progression of the disease in an attempt to prevent a shortage of medical resources. While some countries reacted fast, others waited a tad too long before taking the appropriate measures and are now facing an unprecedented health crisis. In any cases, the result of this pandemic is a massive disruption in the personal and professional activities of a majority of the world's population. 

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Topics: Sample preparation, Tips, Mass spectrometry, Controls, Digestion efficiency

PhenoSwitch moved in a brand new lab!

Posted by Jean-Philippe Couture, Ph.D. on February 25, 2020

Sometimes, you have to move to go forward..

Well, we were kind of in that situation last year! However, we are very proud to announce that we have been operating our machines in our new space in beautiful Sherbrooke (Quebec, Canada) for almost a year now. With our growing client base and an urgent need for privacy, we needed to find a new home for our TTOF5600 and several new mass spectrometers.

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Topics: Mass spectrometry, LCMS-8060, News, TripleTOF6600

Why you should control the digestion step in your proteomics experiments

Posted by Jean-Philippe Couture, Ph.D. on February 14, 2020

Controls, controls, controls!

Over the last two decades, extensive technological and methodological advances have led to the widespread use of mass spectrometry (MS)-based bottom-up proteomics, which involves the digestion of proteins into peptides followed by identification and quantification of the resulting peptides by LC-MS.  MS based analysis is the method of choice for large-scale exploration of proteomes in biological systems and has significantly contributed to the comprehension of a variety of biological processes. In the field of clinical research, quantitative MS has been an integral part of numerous biomarker discovery and evaluation studies1.

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Topics: Sample preparation, Tips, Mass spectrometry, Controls, Digestion efficiency

General terms of services

Posted by Jean-Philippe Couture, Ph.D. on August 8, 2019

1. General terms

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Topics: Mass spectrometry, LCMS-8060, News

How to ship your samples to PhenoSwitch

Posted by Jean-Philippe Couture, Ph.D. on October 18, 2017

Simple rules to ensure successful delivery of your samples

Here we are! The quote has been approved and signed. You are excited to finally get MS results for your project and start thinking about shipping your precious biological samples to PhenoSwitch. Since we're all about getting your samples in the best possible condition, we decided to write some of the rules that should be followed to ensure proper shipment of your package to Canada (if you are outside Canada)! Customers shipping from the US from whom international shipping can be an issue, please refer to this alternative shipping route.

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Topics: Sample preparation, Mass spectrometry, Sample shipping, shipping samples to PhenoSwitch

7 reasons to consider outsourcing some parts of your research

Posted by Jean-Philippe Couture, Ph.D. on April 6, 2017

Faster, bigger, better: Scientific discovery is following that trend too!

Whether we like it or not, our beloved scientific community is getting pushed by the same productivity rules as the other disciplines. In order to be successful, researchers and pharma are expected to deliver solid, innovative and impactful research, faster than ever. Moreover, the trend of multidisciplinary research and the fast growth of the new technologies in these fields make it more and more difficult for a lab to keep up with the pace. In order to stay relevant, smaller labs often have to collaborate with other research teams to build bigger projects that are viable. But as we all know it, even with the best of intentions, bad communication between different research groups can hold back the propagation of useful results. Also, not everyone in a research collaboration has the same priority for the project. Therefore, as powerful as it is, collaboration can be hard to achieve without any drawbacks.

Escaping from bad communication that slows your progress is one of the many reasons why outsourcing could help your research project. But what are the cost-to-benefits ratio of outsourcing some or all parts of your research? What does it cost, will it be done the way you want it to be and what about the privacy/secrecy of your data? At first look, there seems to be more reasons to not outsource your work, but consider this--in September of 2016, Science, one of the industry’s most influential scientific journal, published a paper on outsourcing as being one of the next major trends in scientific research. As a service provider ourselves, we also feel that you should have a more in-depth look at the matter.

So here it is: 7 reasons why you should consider outsourcing your lab work!

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Topics: Mass spectrometry, ECommerce, Outsourcing

Attention aux arnaques : votre remède naturel est-il vraiment naturel? [French version]

Posted by Jean-Philippe Couture, Ph.D. on March 7, 2017

Une note amicale de vos serviteurs chez PhenoSwitch: votre naturopathe improvisé n'est peut-être pas aussi naturel qu'il le prétend. Here's a link to an english version of this post. 

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Topics: Lipidomics, Mass spectrometry, High Sensitivity

Beware of the scams : is your herbal medicine really natural?

Posted by Jean-Philippe Couture, Ph.D. on March 7, 2017

A friendly note to the "all-natural medicine" preachers from the folks at PhenoSwitch: your improvised store herbalist may not be that natural after all. Also, for our French-speaking readers, we wrote a special "version française de ce blog ici".

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Topics: Lipidomics, Mass spectrometry, High Sensitivity

A shiny new QTRAP 6500+ in our labs!

Posted by Jean-Philippe Couture, Ph.D. on February 28, 2017

Better sensitivity, better linearity and better selectivity with the QTRAP 6500+ from SCIEX

Sometimes, we don't need all that power. But sometimes, it takes the very best to get what we are after. We are happy to announce that we can now deliver the very best in sensitivity, linearity and selectivity for your mass spectrometry analyses. Our latest toy, the QTRAP 6500+ from Sciex, is fresh out of the box and ready to rock! 

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Topics: Lipidomics, Mass spectrometry, High Sensitivity, QTrap 6500+, Small molecule, Method development

10 reasons why you should choose mass spectrometry to study your molecule of interest

Posted by Jean-Philippe Couture, Ph.D. on September 7, 2016

Why should I use mass spectrometry in my research project?

It is no secret that mass spectrometry can be very intimidating for new users. For a lot of biologists and physicians, MS represents a shadow of a memory, in a distant undergraduate class. We all heard the terms TOF or MALDI-TOF, and remember that it means Time-of-flight and something-something-laser(!)-Time-of-flight, but for the majority of us, that's about it. We think that the mass spectrometer spits out thousands of numbers in a spreadsheet, and that if you are not sitting with the scientists who performed the analysis, you won't be able to get anything meaningful out of this mess. Also, it costs money. A lot of money.

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Topics: Sample preparation, Mass spectrometry

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